Even with the mixed evidence, we see a lot of clinical efficacy from prazosin; just watch the blood pressure, and we try not to touch blood pressure right away because in our experience we do not need to. How much to use depends a lot on the individual.
When we reach for it
Even with the mixed evidence, we see a lot of clinical efficacy from prazosin. Just watch the blood pressure.
“Prazosin, as you know, even with this mixed evidence, I see a lot of clinical efficacy. Just watch that blood pressure”
52:26Insomnia and Sleep Medications in PsychiatryDec 2024 We try to avoid messing with blood pressure right away, because in our experience we do not need to.
“I personally try to avoid messing around with the blood pressure right away because I've found in my experience I don't need to”
13:13PTSD Medications: Integrating Pharmacotherapy, Therapy, and the Treatment Frame | Episode 22Apr 2025
Dosing and titration
How much to use depends a lot on the individual. In the study of mostly male veterans, we believe they went up to seven or eight milligrams, which is pretty high.
“Don't forget that how much prazosin you're supposed to use depends a lot. on the individual, right? When they did the study on male veterans, mostly male veterans, I believe they were going up to seven or eight milligrams, pretty high”
12:08PTSD Medications: Integrating Pharmacotherapy, Therapy, and the Treatment Frame | Episode 22Apr 2025
From these episodes
- PTSD Medications: Integrating Pharmacotherapy, Therapy, and the Treatment Frame | Episode 22Apr 2025 · 2 points
- Insomnia and Sleep Medications in PsychiatryDec 2024 · 1 point
Every point above is something said on the Psychofarm podcast, with the words as spoken and a link to the moment in the episode. It is education, not medical advice, and an episode reflects what we thought when we recorded it.