What We’ve Said

What we’ve said about Selegiline

1 points from 1 episode, newest first

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In short

The selegiline patch is absorbed systemically rather than through the gut, so in theory it carries a much lower risk of a hypertensive reaction to tyramine-containing foods. Even so, we think following the diet is still recommended.

Side effects and safety

  1. The patch is absorbed systemically, not through the gut, so in theory there is much less risk of a hypertensive reaction to tyramine-containing foods. We think following the diet is still recommended.

    “Because the patch is absorbed systemically and not through the gut, there's a much lower risk of the tyramine reaction. That's right. Theoretically, and I think it's still recommended to follow the diet, but theoretically, there's less risk of the hypertensive reaction from tyramine-contained foods”
    42:13Psychiatrist's Guide to Anxiety Medications: First Line to Last ResortJun 2025

From these episodes

Every point above is something said on the Psychofarm podcast, with the words as spoken and a link to the moment in the episode. It is education, not medical advice, and an episode reflects what we thought when we recorded it.

Educational content only. Everything here is what was said on the Psychofarm podcast, for clinicians. It is not medical advice and not a substitute for clinical judgment, current labeling or guidelines. An episode reflects what we thought when we recorded it, so check anything before you rely on it.