A personality disorder is an inflexible pattern of relating to oneself and others, rooted in development, and it is the most neglected category in psychiatry: treatment-resistant depression is where it goes to hide. Diagnose it from the life course rather than vibes or countertransference, think in traits and levels of functioning rather than ten boxes, explain it kindly, and treat the core with psychotherapy rather than more medication.
What it is
Personality is a collection of habits and responses in how we react to other people, ourselves and situations, shaped both by what we are born with and by development.
“a personality, in as brief as I can say it, is a collection of habits and responses that in terms of how we react to other people, ourselves, and situations, that is both informed by the characteristics we're born with and by our development”
6:09Assessment of Personality: Practical Assessment in a Short TimeframeMay 2025 Most personalities have some adaptability. A personality disorder is a lack of flexibility in how the person responds to their environment, and that inflexibility of defenses is fundamental. An unusual belief, like astrology, is not the point.
“A big part of the definition of a personality disorder is that most personalities have some degree of adaptability, and personality disorders is a lack of flexibility with how they respond to their environment”
28:34Assessment of Personality: Practical Assessment in a Short TimeframeMay 2025 Also said in 1 more episode
“a fundamental part of personality disorders is the inflexibility of those defenses. I remember in residency, I had like classmates who were saying that someone was Are they personality pathology because they believe in astrology”
21:42Healthy Personality Traits, Trauma vs. Personality, and Why Trauma Doesn’t Explain It AllOct 2024 Trauma, both clear trauma and less clear emotional difficulties, interferes with the development of self and relationships, and that is the root of personality disorders. Most personality disorders are probably a mixture of neurodevelopmental and trauma disorders.
“trauma, properly, proper trauma, really clear trauma, and also not so clear traumas, emotional difficulties, clearly interfere with the process of self and relationship development. And that's the root of the personality disorders”
23:51Healthy Personality Traits, Trauma vs. Personality, and Why Trauma Doesn’t Explain It AllOct 2024 Also said in 1 more episode
“it's basically i i like to think that most personality disorders are a mixture of neurodevelopmental and trauma disorders”
54:51ADHD Again, But Juicier: Unpacking Misdiagnosis, Medication Overuse, and Cultural TrendsOct 2024 Personality pathology does not require a parent who fully neglects or abuses the child. Attunement is a really helpful concept here.
“Personality pathology doesn't develop from a parent who necessarily fully neglects or abuses their child. Attunement is a really helpful concept here”
24:59Healthy Personality Traits, Trauma vs. Personality, and Why Trauma Doesn’t Explain It AllOct 2024 In complex developmental trauma, the injury is not a fear response circumscribed to the trauma. It is a wholesale inhibition or change of the person's personality.
“the injury is not to some fear response and understanding of the world issue that circumscribed to the trauma it's a wholesale inhibition or change of this person's personality due to developmental issues”
20:46CPTSD vs BPD: How to Think About the Difference and What to Do About ItMar 2026 It is clinically implausible for someone with a multi-trauma, terrible developmental life from early childhood onward to have normally functioning personality.
“it is totally implausible for someone who has a multi-trauma terrible developmental life from early childhood onwards to have a normal functioning personality. It's completely clinically implausible”
39:50Assessment of Personality: Practical Assessment in a Short TimeframeMay 2025 The different personality disorders are different flavors, and each can operate in the neurotic, borderline or psychotic range.
“So all the different subtypes, all different personality disorders are different flavors, and they can all operate in the neurotic, borderline, or psychotic range”
27:53Is Psychoanalysis Still Relevant in Modern Psychiatry?Oct 2025 Without the theory and history, borderline personality disorder looks like a very special entity few people have, instead of a common, broad spectrum of developmental problems.
“If you don't understand the fundamental theory and history behind borderline personality disorder, you're going to think it's one very special entity that only a small amount of people have. Instead of it being a basically common broad spectrum area of problems that people have through development”
18:15Is Psychoanalysis Still Relevant in Modern Psychiatry?Oct 2025 We all operate at different levels of functioning and regress, breakups being a big one. Splitting the world into heroes and villains is the original state of mind for all of us; we only pretend we are not doing it.
“It comes natural to all of us. It's the original state of mind. And we only pretend that we're not doing it”
19:20Healthy Personality Traits, Trauma vs. Personality, and Why Trauma Doesn’t Explain It AllOct 2024 Also said in 1 more episode
“We all have the ability to operate at different levels of functioning. And if you are honest with yourself, you'll see that there's a ton of times in your lives that you regress. During breakups, that's a big one”
22:03What Psychiatrists Get Wrong About Personality DisordersOct 2024 There is debate over whether to define personality disorders by traits, severe traits or interpersonal functioning. A hybrid approach is probably best.
“whether we should define disorders as traits only, severe traits, or whether it's a matter of interpersonal functioning. I think a hybrid approach is best, but I tend to try to split the difference”
48:59The Psychology of Elizabeth Holmes in You Can See Everything: Narcissism, Autism, or Manipulation?Oct 2026 One stronger view: the only things we should consider personality disorders are those that fit under borderline personality organization.
“the only things that we should consider are personality disorders are things that would fit under the category of borderline personality organization”
35:08What Psychiatrists Get Wrong About Personality DisordersOct 2024
Course and age
A personality disorder at any age is not a lifetime sentence. You can stop meeting criteria, especially with treatment.
“a personality disorder at any age is not a lifetime sentence. You can stop meeting criteria for a personality disorder, especially with treatment”
3:51Healthy Personality Traits, Trauma vs. Personality, and Why Trauma Doesn’t Explain It AllOct 2024 The counterpoint on age: trying to figure out identity is developmentally appropriate in early adolescence, but still doing it at 35 is not.
“if you're 35 and you're still trying to figure out those things, those are behaviors that are not developmentally appropriate”
5:08Healthy Personality Traits, Trauma vs. Personality, and Why Trauma Doesn’t Explain It AllOct 2024 When personality improves over time, it comes from opportunity, development and changes in the underlying biology.
“For a personality, at least, I think it's because it's opportunity development and changes in the underlying biology”
29:41Bipolar Misunderstandings, Integrating Biology & Personality, & Broader ConceptualizationsSep 2024
How we diagnose it
Assess in two steps. First listen in a sensitive but non-specific way for signs of personality pathology in the visit, the interaction and the history; once enough signs have accumulated, move to something more specific.
“We want to first listen carefully in a way that's more sensitive but not specific for signs of personality pathology within the visit, within interaction, and also in the history. And then once enough of those signs have been marked as present, In our minds, we go to something more specific”
13:58Assessment of Personality: Practical Assessment in a Short TimeframeMay 2025 Use both the state in front of you and the course from the history, particularly the course, because a personality disorder should be present across settings and with different people.
“I think it's very important to make sure that you're utilizing data from both the state in front of you in visits and also the course based on the history, and particularly the course. Because, again, a personality disorder is supposed to be something that is present across settings and with different people”
11:46Assessment of Personality: Practical Assessment in a Short TimeframeMay 2025 Do a mental status exam: what they say and don't say, how they act, and how they interact with you. Practice asking yourself, for every patient, what was it like to be with this patient?
“You should be doing a mental status exam, right? You observe the patient and how they act, what they say and what they don't say, in addition to the literal information that they're telling you. On top of that, you observe how they interact with you”
15:06Assessment of Personality: Practical Assessment in a Short TimeframeMay 2025 Also said in 1 more episode
“one of my mentors would always ask during staffing, okay, but what was it like to be with this patient, okay? That's an important question to ask yourself simply as practice with every particular patient”
20:09Assessment of Personality: Practical Assessment in a Short TimeframeMay 2025 Personality diagnosis relies on an honest, relatively thorough account of the patient's psychosocial life and development, which takes time. Any diagnosis reached quickly carries lower certainty; a diagnosis is only as good as its database.
“the diagnosis personality truly relies very strongly on getting a honest and relatively thorough accounting of the patient's psychosocial life and their course in development. And yeah, that's going to take some time”
21:16Assessment of Personality: Practical Assessment in a Short TimeframeMay 2025 Also said in 1 more episode
“any diagnosis that you reach with short time you have to know that you're doing that with a lower degree of certainty than one that you've reached over time and from testing and retesting so just keep that in mind your diagnosis is only as good as the database that you're working with”
13:04Assessment of Personality: Practical Assessment in a Short TimeframeMay 2025 When personality is suspected, dig into work history, conflicts, firings, arrests, how many relationships and how long they usually last.
“if you're a suspecting personality, then you're going to want to have a deeper dive into work history, history of conflicts, firings, arrests, you know, How many times you've been in a relationship, how long does it usually last”
40:30How to Do a Psychiatric Intake | The Art and Science of the First HourSep 2025 Ask open questions and let the patient talk, for example: do your relationships with people you really care about have a lot of extreme ups and downs? You are not looking for a yes or no.
“You literally might just ask, do your relationships with people that you really care about have a lot of extreme ups and downs? And you have the patient talk. We are not looking here for a yes or no response”
41:24Assessment of Personality: Practical Assessment in a Short TimeframeMay 2025 Listen for discrepancies, such as an absolutely perfect relationship in which the partner cheated a lot.
“they'll talk about this amazing relationship that was absolutely perfect. And then as they talk about more, you'll hear real discrepancies talking about how the relationship was perfect, but the partner cheated a lot”
37:16Assessment of Personality: Practical Assessment in a Short TimeframeMay 2025 Listen for lower-level defenses such as generalized paranoia: always guarded, watching for people taking advantage of them or trying to harm them.
“some lower level defenses that can be quite present. in people with lower level personality functioning are general paranoia. It's just a generally paranoid person. Are they always kind of guarded, looking out for people, taking advantage of them or trying to harm them”
47:20Assessment of Personality: Practical Assessment in a Short TimeframeMay 2025 Recurrent self-harm signals aggression directed at oneself; physical or verbal fights signal aggression directed at others.
“If there is recurrent self-harming behaviors, that is a sign of a tendency towards aggression and a tendency to direct aggression towards themselves and also other directed aggression will be meaningful right fights physical verbal”
45:48Assessment of Personality: Practical Assessment in a Short TimeframeMay 2025 In severe impairment, the capacity for positive, enduring connections is significantly impaired: on-and-off relationships, dropping people for years and then being intensely involved with them.
“the capacity for positive and enduring connections is significantly impaired. This is when you see the on and off again kind of quality to the relationships, right? Dropping some people even for years and then intensely being involved with them”
59:53Assessment of Personality: Practical Assessment in a Short TimeframeMay 2025 Regular heavy drug use from a young age often indicates problems regulating emotional experience, and a persistent substance use disorder with a total absence of personality pathology is very hard to find. People with good self-direction and emotional regulation find more productive ways of coping.
“it is unfortunately the case that, at least up until recently, Most people don't use a lot of drugs regularly from a younger age, and I would actually say that that behavior is often indicated of problems with regulation of emotional experience”
29:26Assessment of Personality: Practical Assessment in a Short TimeframeMay 2025 Also said in 1 more episode
“It's very hard to have that maintained in a person and have total absence of personality pathology because in a way it's just wrapped up. People who have good self-direction and emotional regulation, they find other ways of coping that are a little bit more productive”
31:28Assessment of Personality: Practical Assessment in a Short TimeframeMay 2025 Violent impulses that come from personality tend to be ego syntonic. Examine further when there is distress or no clear link to secondary gain.
“people who have a lot of violent impulses that is fundamentally related to personality tends to be ego syntonic it tends to be ego syntonic you should examine when there seems to be some kind of a distress or if there's not a clear link to a secondary gain”
48:28Practical OCD Psychopharmacology: Evidence‑Based (& Non Evidence-Based) Medication ApproachAug 2025 Personality is always active clinically, but it is rarely sufficient on its own to explain someone presenting acutely.
“personality is always active clinically, but it's also not sufficient to explain someone who is presenting more acutely. OK, it's basically rarely sufficient to explain that”
32:41Disability Claims 101 for Psychiatrists: Programs, Pitfalls, and Practical StepsDec 2025 Watch for mismatches. A high level of persistent achievement that does not fit apparently psychopathic, assaultive behavior suggests something other than a personality problem is driving it.
“it was a high level of achievement and persistence in achievement that did not match the kind of apparently psychopathic assaultive behavior that is usually the product of a personality disorder or a personality problem. So that was a mismatch there”
2:14Assessment of Personality: Practical Assessment in a Short TimeframeMay 2025 Psychological testing is just a tool for the same diagnostic process. The DSM-5 also has self-assessment measures you can give patients.
“remember, psychological testing results is just a tool. that helps you do the same diagnostic process that I just talked about. The DSM-5 also has some measures of self-assessment that you can give patients”
53:41Assessment of Personality: Practical Assessment in a Short TimeframeMay 2025 To know what normal answers sound like, be careful: you and your friends may share a personality, and without enough self-insight you won't tell whether responses are normative.
“you have to be careful because you may have a certain personality and your friends are all mostly of a certain personality. And if you don't have enough self-insight to notice that, then you won't be able to tell whether or not the responses are normative or not”
27:56Healthy Personality Traits, Trauma vs. Personality, and Why Trauma Doesn’t Explain It AllOct 2024
Categories, traits and the alternative model
People rarely fit into one of ten personality styles. Most are better described by specific traits and general personality dysfunction, and for most the most appropriate diagnosis is probably other specified personality disorder, with traits of several disorders reflecting core problems in self and interpersonal functioning.
“Most people are probably better described as having certain specific traits and general personality dysfunction. It's in the DSM. People just don't necessarily read it”
20:21Is Psychoanalysis Still Relevant in Modern Psychiatry?Oct 2025 Also said in 2 more episodes
“If you actually learn people, they rarely fit into one. It's not like there's these 10 personality styles that everyone fits into. Now, the alternative model is a little bit better because it's more dimensional”
9:15Assessment of Personality: Practical Assessment in a Short TimeframeMay 2025 “the most appropriate diagnosis in personality disorders for most people is probably an other specified personality disorder where they have traits of multiple personality disorders, which is the manifestation of the core problems with self and interpersonal functioning”
42:59Assessment of Personality: Practical Assessment in a Short TimeframeMay 2025 The categories in the main section of the DSM are terrible. The DSM-5 alternative model in Section III is very good and worth getting familiar with, yet few clinicians have read it or the general personality disorder text.
“What percentage of you have gone to section three and read the alternative model for DSM personality disorders? And again, the general personality disorder text”
20:04Is Psychoanalysis Still Relevant in Modern Psychiatry?Oct 2025 Also said in 1 more episode
“the personality disorder categories as described in DSM are terrible in the primary section, not the alternative model, by the way, section three. The DSM-5 has an alternative model that I think is very good and that people should be really familiarizing themselves with”
30:08What Psychiatrists Get Wrong About Personality DisordersOct 2024 The alternative model is not hypothetical: it is an APA-approved DSM system, considered as valid as the traditional model. It centers pathology on personality functioning, meaning self functioning and interpersonal functioning.
“it's alternative because it's not hypothetical. It's considered a coexisting and as valid model as the traditional DSM-IV model for personality disorders. This is a DSM system, you know, APA approved”
5:35Assessment of Personality: Practical Assessment in a Short TimeframeMay 2025 Also said in 1 more episode
“The alternative model centers to pathology of personality around, uh, personality functioning, which is about how we relate to ourselves and others. Interpersonal functioning and self functioning”
41:46Bipolar Misunderstandings, Integrating Biology & Personality, & Broader ConceptualizationsSep 2024 Look at criterion A and level of personality functioning. One of us has hardly made a borderline diagnosis in two years, and instead points to maladaptive traits or problems of personality functioning.
“if we simply look at criterion a and we look at level of personality functioning i don't know if i've made a borderline personality disorder diagnosis in the last two years okay most of the time i just point to maladaptive personality traits or problems of personality functioning”
34:28CPTSD vs BPD: How to Think About the Difference and What to Do About ItMar 2026 At level three, severe impairment, with at least two domains impaired, it is clearly a personality disorder.
“Now, let's go to level three. That's severe impairment. This would be clearly if you have at least two domains impaired personality disorder”
57:50Assessment of Personality: Practical Assessment in a Short TimeframeMay 2025 In forensic work the alternative model is not very practical, especially for one-off evaluations, though it remains important.
“in forensics, as much as I'm a fan of the alternative model, it's not very practical for use, especially for one-off evaluations, yet it's still so important”
16:09Healthy Personality Traits, Trauma vs. Personality, and Why Trauma Doesn’t Explain It AllOct 2024 The 1980 DSM shift, well intentioned, made a categorical system of discrete, present-or-absent criteria.
“when the DSM made its paradigm shift in 1980, it decided, for various reasons that were very well-intentioned, that it wanted to make a categorical nosology or categorical taxonomy, meaning that you'd have present versus absent criteria, and they would be discrete criteria”
5:31Nancy McWilliams on Psychoanalytic Diagnoses, Part 1: Personality, Defenses, Themes, Paranoid PersonalityNov 2024Guest episode Depressive personality was the most common type in the pre-1980 literature, the empirical literature included, but the mood disorders task force did not want it in the DSM.
“the most common kind of personality type that existed in the literature, including the empirical literature before 1980, was depressive personality. But people on the mood disorders task force didn't want to have depressive personality in there”
7:09Nancy McWilliams on Psychoanalytic Diagnoses, Part 1: Personality, Defenses, Themes, Paranoid PersonalityNov 2024Guest episode Late in his career, Gunderson argued for separating borderline and antisocial, the major personality syndromes, from the rest: list those on Axis I and let the trait psychologists dimensionalize everything else. Narcissism and obsessionality (OCPD) sit on dimensions, while borderline and antisocial stay distinct syndromes.
“John Gunderson, by the way, towards the end of his career, argued that we needed to separate borderline and antisocial from the rest of the personality disorders. Those were the major personality syndromes. List those on axis one and let the trait psychologists dimensionalize everything else”
41:16Diagnostic Hierarchy Explained: Why Patients Get 5 DiagnosesNov 2026Guest episode Also said in 1 more episode
“Narcissism is on a dimension, OCPD, obsessionality is on a dimension, but borderline and antisocial syndromes retain those”
41:33Diagnostic Hierarchy Explained: Why Patients Get 5 DiagnosesNov 2026Guest episode
What it gets confused with
Autism versus personality disorder comes down to inability or lack of interest: is it difficulty understanding the emotions of others, or not caring to?
“is that personality or is it simply that they lack conscious understanding or have a lot of difficulty understanding the emotions of others? Right. Is it inability or lack of interest? That's the dividing line. We want that dividing line between autism and personality disorders”
38:07The Psychology of Elizabeth Holmes in You Can See Everything: Narcissism, Autism, or Manipulation?Oct 2026 Many patients with personality disorders feel a neurodevelopmental label fits them better, and a clinician should be able to tell when personality pathology is what is going on.
“I see a lot of patients with personality disorders who feel the neurodevelopmental label fits them better. For a clinician to be able to easily tell that it's not a neurodevelopmental issue, there's personality pathology kind of going on”
15:12Autism Diagnosis Explained: DSM-5 Criteria, Autistic Traits & the Difficult DifferentialSep 2026 There is a large mutual blind spot between those who recognize personality disorders and those who recognize autism, with too little coordination in research or clinics.
“there is a large mutual blind spot between both clinicians and researchers who are interested in and recognize personality disorders on one hand and neurodevelopmental disorders like autism spectrum on the other hand. There's not enough coordination between these groups in research or clinical settings”
15:31Autism Diagnosis Explained: DSM-5 Criteria, Autistic Traits & the Difficult DifferentialSep 2026 The DSM notes that autism behaviors can be perceived as narcissistic, schizotypal or schizoid personality, and the opposite is true too.
“the DSM actually specifically notes that behaviors associated with autism spectrum disorder can be perceived as symptoms of narcissistic, schizotypal, or schizoid personality. And that schizoid, sorry, schizotypal personality I'm going to say that's absolutely true, and the opposite is true too”
30:45Autism Diagnosis Explained: DSM-5 Criteria, Autistic Traits & the Difficult DifferentialSep 2026 Much of what social media calls ADHD (present in many with true ADHD) is better attributed to depressive disorders, trauma disorders and personality; many of those conceptualizations are describing a personality disorder and calling it ADHD.
“a lot of what is popularly referred to as symptoms of ADHD on social media, while, yes, present in many people with true ADHD, generally speaking, what they're talking about, that symptom cluster is better attributed to depressive disorders, trauma disorders and personality”
33:00ADHD Is Not the Only Diagnosis: Differential and Diagnostic HierarchyNov 2025 Also said in 1 more episode
“many at least uh social media conceptualizations of adhd are describing a personality disorder as class you're gonna you are and just calling it adhd”
54:04ADHD Is Not the Only Diagnosis: Differential and Diagnostic HierarchyNov 2025 The DSM itself says that in adolescents and adults ADHD may be hard to distinguish from borderline, narcissistic and other personality disorders. Older editions named it explicitly as an explainer, and the DSM-5-TR still lists it in the differential.
“in older editions of the DSM, it was explicitly mentioned as one of the possible explainers that isn't ADHD for the presentation. And keep in mind that it's still discussed under the DSM-5TR under the differential diagnosis area”
54:50ADHD Is Not the Only Diagnosis: Differential and Diagnostic HierarchyNov 2025 Also said in 1 more episode
“In adolescents and adults, it may be difficult to distinguish ADHD from borderline, narcissistic, and other personality disorders”
51:54ADHD Again, But Juicier: Unpacking Misdiagnosis, Medication Overuse, and Cultural TrendsOct 2024 Adult difficulties that suggest problems with self-direction (dropping out, not pursuing what they wanted, many different jobs and interests) and identity point toward personality.
“we're hearing about somebody whose difficulties across their adult life suggest problems in self-direction okay uh dropping out of school not pursuing the thing that he wanted to to begin with having a variety of different jobs and interests identity”
12:02How to Decide When ADHD Is Actually ADHDNov 2025 We separate social and separation anxiety from avoidant and dependent personality even though the phenomenon is basically the same.
“We separate out social anxiety and separation anxiety from dependent and avoidant personality, even though the phenomenon is basically the same”
23:59Understanding Anxiety, GAD, and Treatments of AnxietyJun 2025 For depression, ask whether the low mood is there no matter what is happening, or mostly in the context of bad feelings between the person and others and in how they relate to themselves.
“Is it there no matter what's happening in one's life or is it really happening more in the context of bad things happening and bad feelings between you and other people in relationships and in how you relate to yourself”
30:57What Patients Should Know When Diagnosed With DepressionSep 2026 OCD proper means recurrent intrusive obsessions paired with a mental or physical compulsion that is not satisfying, needs a lot of repetition, and often takes at least an hour a day.
“OCD properly should have recurrent intrusive obsessions that are paired to some kind of a mental or physically acting compulsion that is not satisfying know or minimally satisfying or requires a lot of repetition and often takes at least an hour a day of the obsessions and compulsions”
45:33Practical OCD Psychopharmacology: Evidence‑Based (& Non Evidence-Based) Medication ApproachAug 2025 When someone with bipolar disorder seems borderline, the bipolar illness is probably aggravating their underlying personality functioning through stress, regression, irritability or paranoia.
“the bipolar disorder is probably aggravating their underlying personality functioning, right? They're manifesting a lot of those dynamics because they're under a lot of stress or because they're regressed or because they're acutely and supremely irritable or paranoid”
6:15Bipolar Misunderstandings, Integrating Biology & Personality, & Broader ConceptualizationsSep 2024 Bipolar disorder is present early even if the full syndrome waits until the 20s or 30s: irritability, mood changes, problems with concentration.
“bipolar disorders, manic depressive illness, in my experience, even if you don't get the full blown syndrome until the 20s or 30s, it's present early on. There is irritability. There is mood changes. There's problems of concentration”
27:39Bipolar Misunderstandings, Integrating Biology & Personality, & Broader ConceptualizationsSep 2024 The diagnostic hierarchy keeps you from diagnosing a personality disorder before treating mood symptoms that could be exacerbating personality aspects.
“the hierarchy, even if it's simplified and not perfect, makes sure that you don't diagnose conditions that are secondary to another condition, that you're not diagnosing ADHD before treating mood symptoms, which are leading to difficulty with concentrating. You're not diagnosing a personality disorder before treating mood symptoms that could be exacerbating personality aspects”
56:27Understanding Borderline Personality Disorder with Dr. Mark L. RuffaloDec 2024 Call it whatever you want, but give the right treatment. If the mood stabilizer is helping, maybe they do need a mood stabilizer.
“I have my usual message, you know, call it whatever you want, but just give the right treatment. And if your mood stabilizer is helping, maybe they do need a mood stabilizer”
54:05The Best Bipolar Medication Review From The Best Bipolar ExpertJan 2025 Severe personality dysfunction does not always fit neatly into borderline or narcissistic personality disorder, and many providers get stuck on that.
“Like you can have severe personality dysfunction, but not fit neatly into BPD or NPD. So a lot of providers get caught up on that”
33:37CPTSD vs BPD: How to Think About the Difference and What to Do About ItMar 2026 Some patients use the complex PTSD label as a defense against looking at their personality dysfunction. The conversation about traits lets you open that up earlier.
“some patients use it as a defense to not look at their personality dysfunction. And I feel like the McLean screen and the conversation about traits allows me to open up that conversation earlier”
42:56CPTSD vs BPD: How to Think About the Difference and What to Do About ItMar 2026 An otherwise highly functional person with an anger problem is better formulated as one thing causing bigger problems than it needs to, not as a whole broken personality.
“It's not that the whole system of personality is broken. It's this one thing that's causing much bigger problems than it needs to. And then they're constantly kind of making up for it”
20:43Affective Neuroscience: Understanding Patients Beyond DSM DiagnosesAug 2026 A personality disorder can sit behind several apparent diagnoses. Ask whether it is causing depression in the face of rejection or abandonment, anxiety in interpersonal situations, or trouble sleeping because relationships are up and down.
“Does this patient have a personality disorder that might be causing them to become depressed in the face of rejection or abandonment? They might be anxious in interpersonal situations. They might be having trouble sleeping because their relationships are up and down”
50:22Diagnostic Hierarchy Explained: Why Patients Get 5 DiagnosesNov 2026Guest episode The affective temperaments (hyperthymia, cyclothymia, dysthymia) are basically subsyndromal mood disorders found in the family trees of patients with major mood illness, and they are very easily mistaken for personality disorders.
“Hyperthymia, Cyclothymia, Dysthymia, the affective temperaments, which are basically subsyndromal mood disorders that you find in the family trees of patients with major mood illness. These are very easily mistaken for personality disorders”
58:47Diagnostic Hierarchy Explained: Why Patients Get 5 DiagnosesNov 2026Guest episode
Treatment
A personality disorder is functionally a lack of maturation and integration. That is the core pathology, so maturation and integration is the core treatment.
“I think it functionally is a lack of maturation and integration. And so that is the core pathology. And so that's going to be the core treatment”
2:00What Psychiatrists Get Wrong About Personality DisordersOct 2024 Stopping behavior is not the treatment approach; we are used to it only because we conceptualize the pathological side of personality.
“Behavior stopping is not the treatment approach. We're so used to that because we're trying to conceptualize only pathological aspects of personality”
5:18Healthy Personality Traits, Trauma vs. Personality, and Why Trauma Doesn’t Explain It AllOct 2024 Patients with severe impairment have not been taught to repair ruptures together with the other person, which is one reason psychotherapy is so important.
“When there is a fracture, a rupture in a relationship, they have not been taught to, they are not accustomed to repairing that together with the other person, which this is an example of why the psychotherapy is so important in treatment”
1:01:11Assessment of Personality: Practical Assessment in a Short TimeframeMay 2025 Diagnose personality to find the right treatment. If it is not a medication, knowing that prevents harm and wasted time trying to treat a personality problem with medication.
“we want to find the right clinical treatments for people. And if it's not a medication, that's important to prevent harm and to prevent wasting time with trying to treat a personality problem with a medication”
50:51Assessment of Personality: Practical Assessment in a Short TimeframeMay 2025 Depression that comes after a breakup, or shutting down after fights with parents, and that lasts shorter than a mood episode, will not be fixed by throwing different medications at it.
“The depression occurs after a breakup. The shutting down occurs after fights with parents. And they last shorter. They're not these things that last for three weeks. So that if I keep trying to throw different medications, I'm not fixing the underlying problem”
8:16Healthy Personality Traits, Trauma vs. Personality, and Why Trauma Doesn’t Explain It AllOct 2024 With unhealthy personality functioning, tighten your boundaries and make them very strict. A basic formulation of healthy versus unhealthy functioning is enough to guide this.
“The basic gist is, is this person relatively healthy in their personality functioning or unhealthy in their personality functioning? And with patients who are unhealthy, you really need to tighten and have your boundaries be very, very strict”
42:28The Treatment Frame in Action: Lessons from ‘I Fell in Love with My Psychiatrist’Sep 2025 Just as you respect the patient's boundaries, respect your own.
“just as I have to respect their boundaries, I have to respect mine. And there may be times and maybe this is also like, you know, it's it's it's communion and agency and the therapist has both, too”
27:10Why the Therapeutic Alliance Matters in Psychiatry: Recognizing and Repairing Ruptures with Dr. Catherine EubanksNov 2025Guest episode Many patients act out conflicts they are unable to think about because they are so overwhelming.
“a lot of patients act out their conflicts and truly because they're on. It's weird because they're unable to think about them because it's so overwhelming. They act them out”
50:50The Treatment Frame in Action: Lessons from ‘I Fell in Love with My Psychiatrist’Sep 2025 As the neurotic conditions went to biological treatments and CBT, psychoanalytic treatment has become more and more about personality disorders.
“as the, quote, neurotic conditions went to biological treatments and CBT, then the purview of psychoanalysis and psychoanalytic treatments, I think has become more and more the personality disorders”
22:16Is Psychoanalysis Still Relevant in Modern Psychiatry?Oct 2025
Pitfalls and myths
Make sure you have the right diagnosis: treatment-resistant depression is where personality disorders go to hide.
“Make sure you have the right diagnosis, people. Treatment-resistant depression is where personality disorders go to hide”
1:00:44Antidepressant Tier List: Psychiatrists Rank Depression Medications for MDDMay 2026 Saying polypharmacy is the rule risks giving permission to over-medicate personality disorders, with someone on lithium, divalproex and lamotrigine when the diagnosis needs reassessing.
“make sure you have the diagnosis correct because I do fear by saying polypharmacy is the rule, not the exception, that we're giving permission to over-medicate personality disorders or have someone on lithium and Depakote and Lamictal when someone really needs to reassess the diagnosis”
9:10Mood Stabilizers for Bipolar Disorder: Lithium, Lamotrigine, Depakote & MoreJul 2026 Personality is the most clinically neglected category today. What we mostly see is clinicians ignoring it, or diagnosing off vibes and countertransference rather than digging up the clinical data across the lifespan.
“and personality is the most neglected one i'm gonna say personality is the most clinically neglected category today uh but we'll leave that side um”
31:52How to Do a Psychiatric Intake | The Art and Science of the First HourSep 2025 Also said in 2 more episodes
“there is quite a trend in the community of diagnosing off vibes only, off countertransference only. Probably what I mostly see is that they ignore personality”
7:34Assessment of Personality: Practical Assessment in a Short TimeframeMay 2025 “They go off their countertransference rather than digging up and evaluating the clinical data across the lifespan”
57:40Understanding Borderline Personality Disorder with Dr. Mark L. RuffaloDec 2024 The main problem in the clinical treatment of personality is clinician feelings: countertransference about the conditions, about themselves and more.
“The main problem in the clinical treatment of personality, in my opinion, is clinician feelings, the counter-transference feelings about the conditions, about themselves, and about a lot of different things”
42:57Treating Borderline Personality Effectively aka How To Be A Good Psychiatrist Through GPMMay 2025 People want to apply personality disorder diagnoses only to people they dislike, and some clinicians use it to mean "unpleasant person." That is not what it means.
“there's a big problem today in that people only want to apply personality disorder diagnoses to the people they dislike. And they think that the people they like should not have a diagnosis”
53:32The Psychology of Elizabeth Holmes in You Can See Everything: Narcissism, Autism, or Manipulation?Oct 2026 Also said in 1 more episode
“Sometimes I've run to clinicians who don't even really fundamentally understand personality disorders. They really apply the diagnosis like person I don't like or unpleasant person. But that's really not what it means”
25:43The Treatment Frame in Action: Lessons from ‘I Fell in Love with My Psychiatrist’Sep 2025 Patient and provider pretending the treatment is for major depression, while the provider knows there is a personality disorder and does not say so, sets up bad outcomes.
“the patient and the providers making pretend that treatment is major depressive disorder in the back of their mind know that there's a personality disorder, but don't communicate it. And it's really setting up for bad treatment outcomes”
25:20The Treatment Frame in Action: Lessons from ‘I Fell in Love with My Psychiatrist’Sep 2025 Clinicians find major depression and stop, as if they cannot or need not make any other diagnosis. Keep observing, re-diagnosing and re-testing over time.
“So I think what really happens in practice is people go like, I've identified what looks like major depression. Therefore, I can't make any other diagnoses, nor do I need to. And so people really should be longitudinally observing, re-diagnosing, re-testing it”
57:01Understanding Borderline Personality Disorder with Dr. Mark L. RuffaloDec 2024 Clinicians say they do not like to "jump to" a personality diagnosis. Imagine saying that about bipolar disorder, an eating disorder or an anxiety disorder.
“Imagine if you said that about any other diagnosable psychiatric condition. Oh, I don't like to jump to bipolar. Oh, I don't like to jump to an eating disorder. I don't like to jump to an anxiety disorder”
17:17What Psychiatrists Get Wrong About Personality DisordersOct 2024 Most people in inpatient and outpatient clinical populations can meet criteria for a DSM personality disorder. That does not mean it is the main issue.
“studies actually show that for both inpatient and outpatient clinical populations in psychiatry. Most people can meet criteria for a DSM personality disorder. It doesn't mean that's the main issue going on”
15:13What Psychiatrists Get Wrong About Personality DisordersOct 2024 "Just personality" gets said in the emergency room after a difficult interview with someone hearing voices. And doing something on purpose is not the same as having control over it.
“in the emergency room, if someone comes in and says, I'm hearing voices, and then you talk to them and they're a little difficult, it's a difficult interview. Afterwards, you'd say, oh, this is just personality”
13:14What Psychiatrists Get Wrong About Personality DisordersOct 2024 Also said in 1 more episode
“whether or not you do something on purpose is also not the same thing of whether or not you had control over it”
14:16What Psychiatrists Get Wrong About Personality DisordersOct 2024 A lot of severe personality pathology is an internal struggle. These people are not manipulative or causing interpersonal problems; they are struggling inside.
“a lot of severe personality pathology it's it's an internal struggle these people aren't manipulative problematic causing interpersonal whatever they're struggling internally”
18:40What Psychiatrists Get Wrong About Personality DisordersOct 2024 In clinical work we do not diagnose to decide whether something is purposeful or whether the patient is responsible. We diagnose to inform the treatment plan and the patient's treatment targets.
“in a clinical setting, we don't diagnose to decide if something is purposeful or whether the patient is responsible, right? We're diagnosing to inform our treatment plan and to inform the patient of, What are your treatment targets”
19:28What Psychiatrists Get Wrong About Personality DisordersOct 2024 Whether something is biological or psychological has no bearing on whether it is a clinical problem.
“whether or not something is biological or psychological has no bearing on whether it's a clinical problem or not. And we want to medicalize, clinicalize these problems in order to help people”
9:57Healthy Personality Traits, Trauma vs. Personality, and Why Trauma Doesn’t Explain It AllOct 2024 We do not want blame, but productive change is limited if we do not look at how the individual contributes to what is going on.
“We don't want blame, but we do want productive change, and some productive change will be limited in a mild or significant way if we don't look at how the subject, the individual, contributes to what's going on”
13:55Healthy Personality Traits, Trauma vs. Personality, and Why Trauma Doesn’t Explain It AllOct 2024 Ignoring a problem you need to treat does harm too. It is as if stigma against OCD kept us from recommending exposure and response prevention.
“there's also a harm in ignoring a problem that you need to treat. It's as if we had some social stigma against OCD and we didn't want to recommend exposure and response therapy”
6:45Healthy Personality Traits, Trauma vs. Personality, and Why Trauma Doesn’t Explain It AllOct 2024 There is danger in over-interpreting things as Axis I. Thinking in terms of personality gives you more control and more ability to change your surroundings. Everyone has had a personality since birth, and it does change over time.
“So much danger in over-interpreting things as Axis 1. And when you start thinking in terms of personality, you have more control. You have more ability to change your surroundings”
The Psychology of Seinfeld: What’s Really Wrong With George, Kramer, Jerry & Elaine?Aug 2026 Also said in 1 more episode
“everybody on earth has a personality and you've had a personality basically since you were born, even if it wasn't fully formed. And the personality changes over time too, not as much as we'd like maybe, but it does change”
The Psychology of Seinfeld: What’s Really Wrong With George, Kramer, Jerry & Elaine?Aug 2026 Two people with the same DSM diagnosis can have radically different behaviors and lives. Diagnosis is not destiny.
“Two people of the same DSM diagnosis will have radically different behaviors and lives. And I don't know if people understand that diagnosis is not destiny”
The Psychology of Seinfeld: What’s Really Wrong With George, Kramer, Jerry & Elaine?Aug 2026 Vague heuristics get a few major personality disorders diagnosed, and then clinicians assume medications won't work.
“Most people use vague heuristics to diagnose just a few of the major personality disorders, and then from there feel as though medications won't work”
7:18Assessment of Personality: Practical Assessment in a Short TimeframeMay 2025 Excluding personality disorders from "mental illness" for commitment is a legal reality, not a clinical one; you could even call it a legal fiction in some places.
“traditionally traditionally mental illnesses did not include things like personality disorders because the personality disorders were thought to be fundamental to the person and not independent mental illness per se okay this is not a clinical reality it's a legal reality right you could call the legal fiction even in some places”
18:25Involuntary Treatment & Agency, Thoughts and Feelings | Episode 19Mar 2025 A personality disorder is a medical condition. In theory, a personality disorder alone can qualify someone for SSI.
“Yes. In theory, you can just have a personality disorder and get SSI. So it is a medical condition”
42:44Disability Claims 101 for Psychiatrists: Programs, Pitfalls, and Practical StepsDec 2025 Diagnosing someone from public material is a bridge too far without the data.
“it's a bridge too far to go to diagnosis. We don't have the data for it. I think what's more important to note is that you can watch this stuff and you can say, these are not ordinary people”
47:27You Can See Everything Psychological Analysis by Clinical & Forensic PsychiatristsOct 2026 Making this about us versus them misses that these aspects are part of ourselves. The best writers on personality find the pieces inside themselves that are in other people.
“When we make this stuff about us versus them, we really miss that all these aspects are a part of ourselves. The best writers in regards to understanding personality are the ones who can find the pieces inside of them that are in the other people”
1:04:07The Psychology of Elizabeth Holmes in You Can See Everything: Narcissism, Autism, or Manipulation?Oct 2026
Talking to patients
Explain it plainly: your personality is the way you are used to dealing with yourself and other people, and how you think and feel about both. It comes from what you went through growing up and who you are.
“Your personality is the way that you are used to dealing with yourself and other people and how you think and feel about yourself and other people. And where does that come from? It comes from the things that you went through growing up and who you are as a person”
36:14CPTSD vs BPD: How to Think About the Difference and What to Do About ItMar 2026 Personality is not about being a jerk. It is what you have learned and who you are based on how you were raised and what you have been through.
“personality is not about you being a jerk. Basically, it's what you've learned and who you are based on how you've been raised and the things that you've been through”
23:54Handling Difficult Situations in Psychiatry: ADHD Evaluations, Benzo Requests, Disability Claims, and Involuntary AdmissionsOct 2025 Bluntly telling someone they have a personality disorder can be the most invalidating thing you can do, and many patients will not engage with it.
“Telling someone they have a personality disorder is about the most invalidating thing you can do. Right. I mean, it's it's it's it's frankly insulting. And, you know, a lot of patients aren't going to engage in that”
43:02Affective Neuroscience: Understanding Patients Beyond DSM DiagnosesAug 2026Guest episode The DSM writes its personality disorders as if each category was written by someone quite mad at the patient, which makes them very hard to communicate.
“I think the DSM writes its personality disorders in a way that makes it extremely difficult to communicate to patients because it's as if each diagnostic category has been written by someone quite mad at a patient”
52:32ADHD Again, But Juicier: Unpacking Misdiagnosis, Medication Overuse, and Cultural TrendsOct 2024 If understanding yourself requires a diagnosis that most practitioners will judge negatively and read you through a hurtful lens, looking for another diagnosis is understandable.
“You're telling me that to understand myself, I need a diagnosis that 80% of practitioners are going to negatively judge me and interpret my thoughts, behaviors through this pretty hurtful lens”
14:44Healthy Personality Traits, Trauma vs. Personality, and Why Trauma Doesn’t Explain It AllOct 2024 Be very careful that any diagnosis, especially a culturally laden or emotionally invested one, does not function as resistance to appropriate treatment, consciously or not.
“be very careful about the possibility of any diagnosis, but particularly culturally laden or emotionally invested diagnoses in functioning as a form of resistance to appropriate treatment, consciously or unconsciously for patients”
47:05CPTSD vs BPD: How to Think About the Difference and What to Do About ItMar 2026 Do not be afraid to diagnose personality, and never do it to punish patients. Do it to be a good clinician who correctly identifies what should be treated with psychotherapy and what with medication.
“Don't be afraid to diagnose personality. You're not doing it. You shouldn't be doing it to punish patients. You're doing it because you want to be a good clinician and you want to correctly identify which things should be treated with psychotherapy and which things should be treated with medications”
1:02:00Assessment of Personality: Practical Assessment in a Short TimeframeMay 2025
It also comes up on
- Diagnostic hierarchyAmong the personality disorders, borderline and antisocial are the two that are pretty robustly validated, though personality disorders may belong on the second level rather than the top.
- Affect regulationSevere borderline personality disorder can be understood as lacking the cortical capacity to appraise and modulate intense affective arousal. These patients are pretty much fine until they are not.
- AntipsychoticsIn rare cases an antipsychotic helps in borderline personality disorder, which is hard to explain since the phenomenology differs from schizophrenia. The most severe borderline cases may be a crossover of a severe personality syndrome and a genetic vulnerability.
- Antisocial personality disorderThe antisocial personality disorder diagnosis is not psychopathy. It is purposefully broad, covering a low-grade tendency to break rules and a parasitic lifestyle as well as actual psychopaths.
- Antisocial personality disorderThe insanity defense traditionally excludes antisocial personality disorder. Anyone trained appropriately, who understands why the defense exists and who it applies to, knows it cannot apply.
- Bipolar disorderIt is both overdiagnosed and underdiagnosed: overdiagnosed in patients with a lot of personality pathology such as borderline personality disorder, and severely underdiagnosed in treatment-resistant depression.
- Bipolar disorderMood changes in borderline personality disorder happen in a social context: the trigger is usually an interpersonal event. That is what distinguishes them from depression or bipolar disorder.
- Borderline personality disorderBorderline personality disorder is fundamentally a disorder of contradiction or paradox: the patient is trapped in what the psychiatrist Burnham in the 1960s called a need-fear dilemma.
From these episodes
- Diagnostic Hierarchy Explained: Why Patients Get 5 DiagnosesNov 2026 · 4 points
- The Psychology of Elizabeth Holmes in You Can See Everything: Narcissism, Autism, or Manipulation?Oct 2026 · 4 points
- You Can See Everything Psychological Analysis by Clinical & Forensic PsychiatristsOct 2026 · 1 point
- What Patients Should Know When Diagnosed With DepressionSep 2026 · 1 point
- Autism Diagnosis Explained: DSM-5 Criteria, Autistic Traits & the Difficult DifferentialSep 2026 · 3 points
- Affective Neuroscience: Understanding Patients Beyond DSM DiagnosesAug 2026 · 2 points
- The Psychology of Seinfeld: What’s Really Wrong With George, Kramer, Jerry & Elaine?Aug 2026 · 3 points
- Mood Stabilizers for Bipolar Disorder: Lithium, Lamotrigine, Depakote & MoreJul 2026 · 1 point
- Antidepressant Tier List: Psychiatrists Rank Depression Medications for MDDMay 2026 · 1 point
- CPTSD vs BPD: How to Think About the Difference and What to Do About ItMar 2026 · 6 points
- Disability Claims 101 for Psychiatrists: Programs, Pitfalls, and Practical StepsDec 2025 · 2 points
- How to Decide When ADHD Is Actually ADHDNov 2025 · 1 point
- Why the Therapeutic Alliance Matters in Psychiatry: Recognizing and Repairing Ruptures with Dr. Catherine EubanksNov 2025 · 1 point
- ADHD Is Not the Only Diagnosis: Differential and Diagnostic HierarchyNov 2025 · 3 points
- Is Psychoanalysis Still Relevant in Modern Psychiatry?Oct 2025 · 5 points
- Handling Difficult Situations in Psychiatry: ADHD Evaluations, Benzo Requests, Disability Claims, and Involuntary AdmissionsOct 2025 · 1 point
- How to Do a Psychiatric Intake | The Art and Science of the First HourSep 2025 · 2 points
- The Treatment Frame in Action: Lessons from ‘I Fell in Love with My Psychiatrist’Sep 2025 · 4 points
- Practical OCD Psychopharmacology: Evidence‑Based (& Non Evidence-Based) Medication ApproachAug 2025 · 2 points
- Understanding Anxiety, GAD, and Treatments of AnxietyJun 2025 · 1 point
- Assessment of Personality: Practical Assessment in a Short TimeframeMay 2025 · 27 points
- Treating Borderline Personality Effectively aka How To Be A Good Psychiatrist Through GPMMay 2025 · 1 point
- Involuntary Treatment & Agency, Thoughts and Feelings | Episode 19Mar 2025 · 1 point
- The Best Bipolar Medication Review From The Best Bipolar ExpertJan 2025 · 1 point
- Understanding Borderline Personality Disorder with Dr. Mark L. RuffaloDec 2024 · 3 points
- Nancy McWilliams on Psychoanalytic Diagnoses, Part 1: Personality, Defenses, Themes, Paranoid PersonalityNov 2024 · 2 points
- Healthy Personality Traits, Trauma vs. Personality, and Why Trauma Doesn’t Explain It AllOct 2024 · 14 points
- What Psychiatrists Get Wrong About Personality DisordersOct 2024 · 10 points
- ADHD Again, But Juicier: Unpacking Misdiagnosis, Medication Overuse, and Cultural TrendsOct 2024 · 3 points
- Bipolar Misunderstandings, Integrating Biology & Personality, & Broader ConceptualizationsSep 2024 · 4 points
Every point above is something said on the Psychofarm podcast, with the words as spoken and a link to the moment in the episode. It is education, not medical advice, and an episode reflects what we thought when we recorded it.