A formulation is deeper and richer than a diagnosis: it links causes to effects in plain words, sorts out what is biological, psychological and social, and becomes a story the patient accepts. Without one, clinicians mistake personality for treatment resistance and run patients through ten medication trials. Build it, share it, and get on the same page.
What it is
A formulation is much deeper and richer than a diagnosis and actually gives you an idea of what is going on with a person.
“a formulation to me is much deeper and richer and actually gives you an idea of what's going on with a person”
The Psychology of Seinfeld: What’s Really Wrong With George, Kramer, Jerry & Elaine?Aug 2026 It is the fundamental work of mental health treatment: putting things into words in a way that makes sense and produces causes and effects, and therefore solutions.
“the fundamental work of mental health treatment. It's basically conceptualizing things into words in a way that makes sense and produces causes and effects and therefore solutions, right”
16:27Psychiatric Technique for Diagnostic Interviewing and Therapy: 6 Mantras Every Clinician Should KnowApr 2026 The art of eliciting the right information at the right time and putting it together into a treatment that helps, that the patient will accept, carry through and change with, is the whole of psychiatry.
“the art of eliciting the right information at the right time and putting it together in the right way to get to a treatment that will actually get somebody better and not worse, and that they will accept and carry through with and change with, that's the whole of treatment and psychiatry”
14:08Bipolar Misunderstandings, Integrating Biology & Personality, & Broader ConceptualizationsSep 2024 You cannot get to the right treatment without the right diagnosis or formulation.
“For me, and maybe this is because I was trained in a medical setting, you go from diagnosis to treatment. You have to identify what's going on before you move to how do we help this person”
33:25Diagnostic Hierarchy Explained: Why Patients Get 5 DiagnosesNov 2026Guest episode Also said in 1 more episode
“the idea of right diagnosis right treatment right you're not going to be able to get to a right treatment unless you have the right diagnosis or formulation”
49:23Mindfulness in Psychiatry: How to Teach It as a Clinical Treatment SkillMay 2026 The crux of the work is developing a diagnosis, or at least a formulation if a specific diagnosis is not possible, communicating it and getting on the same page with the patient, then giving treatments that fit.
“a core component of the work I do is I'm trying to develop a diagnosis or at least a formulation if I can't get a specific diagnosis and get on the same page with the patient”
6:30Handling Difficult Situations in Psychiatry: ADHD Evaluations, Benzo Requests, Disability Claims, and Involuntary AdmissionsOct 2025 Also said in 1 more episode
“To me, the crux is figuring out the diagnosis, communicating and being on the same page with the patient, and then giving treatments to fit that diagnosis”
53:00How to Do a Psychiatric Intake | The Art and Science of the First HourSep 2025
How we build it
Every clinically significant depression comes from a biological, psychological or social source, or some combination, sometimes all three.
“every serious or clinically significant depression that anyone can encounter is going to be from a biological source, a psychological source, a social source, or some combination of any of those, and sometimes all three”
8:36What Patients Should Know When Diagnosed With DepressionSep 2026 Conceptualize what you think is more biological, more social and more psychological. The biopsychosocial approach as a label is too simple.
“I think it's responsible in psychiatry still to conceptualize well, each of us, what we think is more biological, what is more social, what is more psychological, not to say that I love the biopsychosocial approach because I think it's too simple”
15:53Bipolar Misunderstandings, Integrating Biology & Personality, & Broader ConceptualizationsSep 2024 Make links between causes and effects and put them together under a name you can refer to with the patient. For example: this trouble concentrating and getting schoolwork done may not be ADHD; it looks like your high level of obsessions, compulsions and anxiety.
“You want to make links between causes and effects and put things together. into some kind of abstract name so that you can refer to it with the patient, regardless of the source”
13:03Psychiatric Technique for Diagnostic Interviewing and Therapy: 6 Mantras Every Clinician Should KnowApr 2026 Also said in 1 more episode
“This problem of concentration you have, this problem focusing and not being able to get the schoolwork done, I'm not so sure it's ADHD. It really does seem like that it's your high level of obsessions, compulsions and related anxiety”
14:06Psychiatric Technique for Diagnostic Interviewing and Therapy: 6 Mantras Every Clinician Should KnowApr 2026 Stay in the interview until you have a story that makes some sort of sense.
“just kind of sitting down in the interview until I have a story that can make some sort of sense is just a helpful guiding principle in interviews”
39:38Lessons from Forensic Psychiatry: Insanity Defense, Subtle Patients and CulpabilityApr 2025 Before calling something a pattern, see it more than twice: twice is a coincidence, three times is a pattern.
“If this is a true pattern, I want to see it more than twice. I like to say twice is a coincidence, three times is a pattern. That's a little conservative, but I want to see more”
14:34The Psychology of Elizabeth Holmes in You Can See Everything: Narcissism, Autism, or Manipulation?Oct 2026 With anxiety in particular, a DSM diagnosis may not cut it, and you may need a full psychotherapy-type formulation to understand the patient's situation.
“with anxiety in particular, DSM diagnosis may not cut it, right? You might have to go on to a full-on psychotherapy-type formulation to really understand the patient's situation”
57:25Understanding Anxiety, GAD, and Treatments of AnxietyJun 2025 A basic personality formulation goes a long way: is this person relatively healthy or unhealthy in their personality functioning? With unhealthy functioning, keep boundaries very strict.
“The basic gist is, is this person relatively healthy in their personality functioning or unhealthy in their personality functioning? And with patients who are unhealthy, you really need to tighten and have your boundaries be very, very strict”
42:28The Treatment Frame in Action: Lessons from ‘I Fell in Love with My Psychiatrist’Sep 2025 Saying a case most resembles a personality problem is not diagnosing a personality disorder, and it is not saying the person does not have ADHD.
“when I say that this most resembles a personality problem, I'm not even saying that's a diagnosable personality disorder. And I'm also not saying that this person doesn't have ADHD”
14:35How to Decide When ADHD Is Actually ADHDNov 2025 Each affect can be described by how much is there at rest, how much when activated, how long it takes to burn off and how much stimulus it takes to set it off.
“there's an amount that when you're just chilling, there's an amount when it gets activated. There's an amount of time that it takes to burn off. And then how much stimulus do you need to kind of get set off”
44:35Affective Neuroscience: Understanding Patients Beyond DSM DiagnosesAug 2026 Make a descriptive diagnosis before jumping to a psychological formulation, because lots of things cause depressed mood: it makes no sense with a brain tumor or a melancholic depression, and a severe recurrent unipolar depression is, we think, primarily a biological disease. Psychological formulation makes a whole lot of sense for abandonment depression, the chronic dysphoria of borderline personality disorder, or what the old psychoanalysts called neurotic depression, which is probably a valid diagnosis.
“before we jump to formulation, we need to have a diagnosis of the patient, a descriptive diagnosis, because lots of things cause depressed mood, right? It doesn't make sense to jump into some psychological formulation if the patient has a brain tumor”
37:41Diagnostic Hierarchy Explained: Why Patients Get 5 DiagnosesNov 2026Guest episode Also said in 2 more episodes
“It doesn't make sense to jump into a psychological formulation if the patient has melancholic depression. If the patient has a severe recurrent unipolar depression, I think that's primarily a biological disease”
37:56Diagnostic Hierarchy Explained: Why Patients Get 5 DiagnosesNov 2026Guest episode “However, if the depression is what James Masterson called abandonment depression, or it's the chronic dysphoria that we see in borderline personality disorder, or it's what the old psychoanalysts used to call neurotic depression, which is probably a valid diagnosis, by the way. Then psychological formulation makes a whole lot of sense”
38:10Diagnostic Hierarchy Explained: Why Patients Get 5 DiagnosesNov 2026Guest episode
Using it in treatment
Set a high threshold for calling depression treatment resistant. Reformulate the patient instead and make sure the work on affect or personality is being done.
“I have a, you know, really high threshold. If someone is not doing well on antidepressants to say that they have treatment resistant depression. I would much rather reformulate the patient. I would much rather make sure we're doing the work on affect or personality”
40:17Affective Neuroscience: Understanding Patients Beyond DSM DiagnosesAug 2026Guest episode Psychoanalysis gives a rich way to formulate, so you think psychologically about a help-rejecting patient instead of simply following the depression medication algorithm.
“It gives a rich way to formulate patients. From the last podcast, the help-rejecting patient example shows the value of thinking psychologically instead of just, you know, the patient has depression, I'm going to follow the medication algorithm”
48:46Is Psychoanalysis Still Relevant in Modern Psychiatry?Oct 2025 The right response to suicidality depends on the patient. For suicidality driven by an adjustment disorder, hospitalization can be the best treatment.
“the correct response to suicidality really depends on the patient. So here, as you're saying, is the best treatment for a patient that has what you're describing, which is an adjustment disorder, is hospitalization”
29:52Suicide Risk Assessment: Acute vs Chronic Risk, Formulation, and Suicidal Ideation TypesJun 2026 In therapy of any kind, formulating and sharing the formulation with the patient is absolutely key.
“Even in a therapy of any kind, I think formulating and sharing that formulation of the patient is absolutely key”
7:09Handling Difficult Situations in Psychiatry: ADHD Evaluations, Benzo Requests, Disability Claims, and Involuntary AdmissionsOct 2025 Only a complex formulation of why people do what they do gives them something actionable, and lets them weigh whether to change themselves or not.
“It's only complex formulation, really getting deeply into why people do what they do. In my opinion, that gets people something actionable and lets you really weigh and deliberate. Should I change myself or not”
The Psychology of Seinfeld: What’s Really Wrong With George, Kramer, Jerry & Elaine?Aug 2026 For a therapist, the diagnosis that matters is the formulation. We wonder how many therapists in the community actively formulate and deliver that formulation to the patient within the first four to six sessions.
“Quote-unquote diagnosis that's pertinent to a therapist is surely the formulation. And then I wonder how many practicing therapists out in the community are actively formulating and then delivering that formulation to the patient within the first four to six sessions”
35:49Diagnostic Hierarchy Explained: Why Patients Get 5 DiagnosesNov 2026
Talking to patients
Save the last 15 minutes or so of the intake for discussing your case formulation. Patients notice you are not a reductionistic doctor.
“I always save the last like 15 minutes for discussing my case formulation. And patients at the end are like, oh, you're definitely not a reductionistic kind of doctor”
52:47How to Decide When ADHD Is Actually ADHDNov 2025 If you can explain the patient's problems so that a completely uneducated person would understand, that is better, because you should formulate with the patient in plain language.
“if you can explain this patient's problems in a way that a completely uneducated person will understand, that's better because that's how you should formulate with the patient in plain language”
29:48Psychiatric Technique for Diagnostic Interviewing and Therapy: 6 Mantras Every Clinician Should KnowApr 2026 Gather enough information together with the patient to string it into a story they are going to accept.
“you need to gather enough information together with the patient to string it together into a story that they're going to accept”
40:36Lessons from Forensic Psychiatry: Insanity Defense, Subtle Patients and CulpabilityApr 2025 Many providers let things go unsaid, and it mucks up the treatment.
“I think a lot of providers have a tendency to let things go unsaid. And it mucks up the treatment”
5:10Handling Difficult Situations in Psychiatry: ADHD Evaluations, Benzo Requests, Disability Claims, and Involuntary AdmissionsOct 2025
Pitfalls and myths
Clinicians who cannot formulate how personality shapes a presentation call everything that does not respond to medication treatment resistance. Patients with 10 or more medication trials are often going through that laundry list because no one made a psychological formulation.
“A lot of clinicians can't formulate how personality shapes a presentation. And then that clinician thinks everything that doesn't respond to meds is some form of treatment resistance”
19:03Is Psychoanalysis Still Relevant in Modern Psychiatry?Oct 2025 Also said in 1 more episode
“I've seen patients with 10 or more medication trials, and the reason why the person's kind of going through this laundry of things that are not going to work is a lack of a psychological formulation”
19:15Is Psychoanalysis Still Relevant in Modern Psychiatry?Oct 2025 We may pretend we are playing a biological game, but we are playing a psychosocial game.
“we may pretend that we're playing a biological game. And we're not. We're playing a psychosocial game”
14:57Bipolar Misunderstandings, Integrating Biology & Personality, & Broader ConceptualizationsSep 2024 Many clinicians are not as able to think psychologically as they were before.
“The loss in terms of, you know, where the question comes from, is it still relevant today, is that many clinicians aren't as able to think psychologically as they were before”
16:13Is Psychoanalysis Still Relevant in Modern Psychiatry?Oct 2025 A bare label can obscure. Call it generalized anxiety disorder or PTSD and ignore the personality and developmental components that belong in the formulation, and the diagnosis robs you of vision rather than giving you clarity.
“a diagnosis can obscure if we simply call it generalized anxiety disorder or PTSD. And then we ignore the personality components, the developmental components, all kinds of components that should belong in that formulation. Then the diagnosis robs us of vision rather than gives us clarity”
36:33Diagnostic Hierarchy Explained: Why Patients Get 5 DiagnosesNov 2026 A therapist can be reluctant to call it borderline personality disorder even when the patient is cutting themselves, has identity diffusion and chaotic, unstable relationships, and devalues the therapist.
“You have a patient who's cutting themselves, identity diffusion, chaotic, unstable interpersonal relationships, devaluing the therapist. And the therapist is reluctant to call that borderline personality disorder”
33:12Diagnostic Hierarchy Explained: Why Patients Get 5 DiagnosesNov 2026Guest episode
It also comes up on
- Borderline personality disorderOne formulation: patients lack the cortical capacity to appraise and modulate intense affective arousal. People with severe BPD are pretty much fine until they are not.
- Childhood traumaTrauma is massively important to your conceptualization, your understanding of the patient and what you are going to do with them.
- Informed consentYour job is to give your formulation and your treatment recommendations and to explain the benefits and the risks, and the risks include not taking the medication.
- Medication managementYour job is to give your formulation and treatment recommendations and to explain the benefits and the risks, and the risks include not taking the medication.
- Psychiatric diagnosisIf a patient pushes back, do not denigrate your own formulation. Build some rapport first and gauge whether the patient will accept it.
- PsychoeducationDo not denigrate your own formulation when a patient pushes back. Build some rapport first and gauge whether the patient is ready to accept it.
- Therapeutic allianceIf a patient rejects your formulation, denigrating it does not help them. Build rapport first and gauge whether they will accept it.
- ADHDCollaborate with the patient, but do not let their justification of a situation end the inquiry. Trust your formulation.
From these episodes
- Diagnostic Hierarchy Explained: Why Patients Get 5 DiagnosesNov 2026 · 7 points
- The Psychology of Elizabeth Holmes in You Can See Everything: Narcissism, Autism, or Manipulation?Oct 2026 · 1 point
- What Patients Should Know When Diagnosed With DepressionSep 2026 · 1 point
- Affective Neuroscience: Understanding Patients Beyond DSM DiagnosesAug 2026 · 2 points
- The Psychology of Seinfeld: What’s Really Wrong With George, Kramer, Jerry & Elaine?Aug 2026 · 2 points
- Suicide Risk Assessment: Acute vs Chronic Risk, Formulation, and Suicidal Ideation TypesJun 2026 · 1 point
- Mindfulness in Psychiatry: How to Teach It as a Clinical Treatment SkillMay 2026 · 1 point
- Psychiatric Technique for Diagnostic Interviewing and Therapy: 6 Mantras Every Clinician Should KnowApr 2026 · 4 points
- How to Decide When ADHD Is Actually ADHDNov 2025 · 2 points
- Is Psychoanalysis Still Relevant in Modern Psychiatry?Oct 2025 · 4 points
- Handling Difficult Situations in Psychiatry: ADHD Evaluations, Benzo Requests, Disability Claims, and Involuntary AdmissionsOct 2025 · 3 points
- How to Do a Psychiatric Intake | The Art and Science of the First HourSep 2025 · 1 point
- The Treatment Frame in Action: Lessons from ‘I Fell in Love with My Psychiatrist’Sep 2025 · 1 point
- Understanding Anxiety, GAD, and Treatments of AnxietyJun 2025 · 1 point
- Lessons from Forensic Psychiatry: Insanity Defense, Subtle Patients and CulpabilityApr 2025 · 2 points
- Bipolar Misunderstandings, Integrating Biology & Personality, & Broader ConceptualizationsSep 2024 · 3 points
Every point above is something said on the Psychofarm podcast, with the words as spoken and a link to the moment in the episode. It is education, not medical advice, and an episode reflects what we thought when we recorded it.